Clinical efficacy of intranasal dexmedetomidine in improving emergence delirium and postoperative maladaptive behavioral changes in children after total tonsillectomy

Clinical study of intranasal dexmedetomidine in improving emergence delirium and postoperative maladaptive behavioral changes in children undergoing total tonsillectomy

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200064539

Enrollment

Unknown

Registered

2022-10-11

Start date

2022-10-11

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tonsil hypertrophy

Interventions

Group 1 :received preoperative intranasal dexmedetomidine 0.05 ml/kg(40 ug/ml)

Group 2:received preoperative intranasal normal saline 0.05 ml/kg

Eligibility

Sex/Gender

All

Age

4 Years to 5 Years

Inclusion criteria

Inclusion criteria: Children with tonsillar hypertrophy who underwent total tonsillectomy only, aged 4-5 years, were ASA grade I-II.

Exclusion criteria

Exclusion criteria: Children with ropivacaine allergy, a history of anesthesia in the last month, a history of sedative use, children with autism, children with ADHD, or children with other psychological disorders diagnosed by a psychiatrist.

Design outcomes

Primary

Measure	Time frame
Pediatric Anesthesia Emergence Delirium scale;the Post Hospitalization Behavior Questionnaire for Ambulatory Surgery;Parental Postoperative Pain Measurement;	—

Secondary

Measure	Time frame
heart rate;mean arterial pressure;pulse oxygen saturation;	—

Countries

China

Contacts

Public ContactYan Lijuan

First Affiliated Hospital of Xiamen University

yanlijuan0122@126.com+86 15710668779

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026