None listed
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged from 2 to 40 years old (including 2 and 40 years old); 2. Have indications for allogeneic hematopoietic stem cell transplantation; 3. Sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Symptomatic coronary heart disease; 2. The physical fitness score is less than 70 points; 3. Cardiac ejection fraction is less than 50%; 4. Creatinine clearance rate is less than 50 ml/min; 5. HCT-specific prognostic index (HCT-CT) greater than 3 (including 3 points); 6. Uncontrolled viral, bacterial and fungal infections (the disease is still progressing during antifungal treatment); 7. HIV seropositive; 8. History of other systemic malignancies; 9. Pregnant and lactating women; 10. Men and women who do not agree to contraception during the trial period; 11. The researcher considers it inappropriate to enroll.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Engraftment incidence;Incidence and extent of graft-versus-host disease; | — |
Countries
China
Contacts
Xiangya Hospital of Central South University