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Effect and central mechanism of personalized repetitive transcranial magnetic stimulation for chronic insomnia disorder

Effect and central mechanism of personalized repetitive transcranial magnetic stimulation for chronic insomnia disorder

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064508
Enrollment
Unknown
Registered
2022-10-10
Start date
2022-10-05
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic insomnia disorder

Interventions

Group 1 :rTMS Targeted with MRI Based Neuro-Navigation
Group 2:No treatment during the waiting period

Sponsors

Chengdu Second People’s Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. CID patients: (1) Meet the diagnostic criteria of ICSD-3 chronic insomnia disorder; (2) Pittsburgh Sleep Quality Index (PSQI) score > 7 points; (3) Age 18 <= age <= 65 years old; (4) Not taking sleeping pills or other psychotropic drugs within 2 weeks before enrollment; (5) The informed consent signed by the patient himself or by his immediate relatives. 2. Healthy control subjects: The inclusion criteria of the healthy control group were similar to those of CID, but without sleep complaints and PSQI score below 7 points.

Exclusion criteria

Exclusion criteria: 1. History of other neuropsychiatric diseases and severe chronic diseases (such as diabetes, heart disease, cancer); 2. A history of substance addiction (such as drugs, nicotine, alcohol); 3. History of epilepsy; 4. Pregnant or lactating; 5. With MRI contraindications; 6. Brain lesions or white matter thickening found by conventional T2-weighted MRI scan.

Design outcomes

Primary

MeasureTime frame
PSQI score;

Secondary

MeasureTime frame
Brain network;Insomnia Severity Index;

Countries

China

Contacts

Public ContactLiang Gong

Chengdu Second People’s Hospital

cd2gongliang@126.com+86 2867830374

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026