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Increasing concentrations of sufentanil according to the cervical dilation used in epidural labor analgesia

Clinical research of sufentanil saving strategy in epidural labor analgesia

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064505
Enrollment
Unknown
Registered
2022-10-10
Start date
2023-11-13
Completion date
Unknown
Last updated
2025-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

labor pain

Interventions

Group of increasing concentrations of sufentainil:Using a solution of increasing concentrations of sufentanil (use a sufentanil concentration of 0.167ug/mL when cervical dilitation less than 6 cm
use a sufentanil concentration of 0.4 ug/mL when cervical dilitation within 6-10 cm) combined with 0.1% ropivacaine.
Group of fixed concentration of sufentanil :Using a solution of fixed concentration of sufentanil (a sufentanil concentration of 0.4 ug/mL) combined with 0.1% ropivacaine in first labor stage.

Sponsors

International Maternity and Child Health Hospital, School of Medicine, Shanghai Jiao Tong University.
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 20-40 years, ASA class 2, full-term ( > 37 weeks' gestation), singleton pregnancy with vertex fetal presentation, cervical dilation of 2-4 cm, visual analog scale scores >= 6 and request for epidural labor analgesia.

Exclusion criteria

Exclusion criteria: Puerperants with obvious cardiopulmonary diseases, contraindications to epidural anesthesia, indications to cesarean section, BMI > 36 kg/m2 were excluded, and patients allergic to local anesthetics or sufentanil were excluded. Maternal refusal was also excluded.

Design outcomes

Primary

MeasureTime frame
Visual analog scale scores of pain;Consumption of sufentanil in latent and active phase of 1st labor stage;PCA times in latent and active phase of 1st stage;time of three labor stages;Provider administered rescue bolus time in latent and active phase of 1st labor stage;

Secondary

MeasureTime frame
Apgar scores;admission to NICU;

Countries

China

Contacts

Public ContactTao Xu

The International Peace Maternity and Child Health Hospital-Shanghai JiaoTong University School of Medicine

towerxutao@163.com+86 189 1809 8660

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026