Comparison of the application of high-flow nasal oxygen with two different oxygen concentrations in infant and child laryngotracheal surgery

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200064500

Enrollment

Unknown

Registered

2022-10-10

Start date

2022-11-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laryngomalacia

Interventions

Intervention group:Oxygen therapy with 70% oxygen concentration

Control group:Oxygen therapy with 100% oxygen concentration

Eligibility

Sex/Gender

All

Age

No minimum to 6 Years

Inclusion criteria

Inclusion criteria: 1. Children scheduled for laryngeal surgery and requiring high-flow oxygen therapy without endotracheal intubation on spontaneous breathing; 2. Aged from 1 month to 6 years; 3. American Society of Anesthesiologists (ASA) Class I-III; 4. Combined with ?-? degree laryngeal obstruction.

Exclusion criteria

Exclusion criteria: 1. Skull and facial fractures; 2. Nasal airflow is significantly blocked due to changes in the nasal septum or nasal cavity; 3. Children requiring neuromuscular block, endotracheal intubation, or mechanical ventilation; 4. CO2 laser is planned; 5. Children with tracheotomy; 6. Combined with grade III-IV laryngeal obstruction.

Design outcomes

Primary

Measure	Time frame
arterial blood gases;minimum oxygen saturation;	—

Secondary

Measure	Time frame
vital signs;operation time;percutaneous partial pressure of carbon dioxide;	—

Countries

China

Contacts

Public ContactXu Ying

Children's Hospital of Chongqing Medical University

xuyingxy3066@126.com+86 13983409393

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026