fetal ventricular septal defect (VSD)
Conditions
Interventions
Gold Standard:Diagnostic criteria of VSD: according to fetal ventricular septal interruption and ventricular horizontal shunt.
Index test:1, Instrument: use GE VolusonE8 or VolusonE10 color Doppler ultrasonic diagnostic instrument, C5-1 or C9-2 convex array probe, probe frequency 1-9mhz, frame frequency control >80 frames /s.
Sponsors
Chengdu Women's and Children's Central Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Single fetus underwent prenatal echocardiography in Chengdu Women's and Children's Central Hospital from July 2022.07-July 2024.07. 2. The gestational age was 22-30 weeks, and the mean gestational age was 26.3±2.3 weeks.
Exclusion criteria
Exclusion criteria: 1. Gestational age >34 weeks or <20 weeks; 2. Irregular menstruation in pregnant women; 3. Fetal chromosome abnormalities; 4. Intrauterine growth retardation of fetus; 5. Pregnant women with gestational diabetes mellitus; 6. Pregnant women with gestational hypertension.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| left ventricular end systolicvolume;left ventricular ejection fraction;left ventricular end diastolic diameter;right ventricular end diastolic diameter;left ventricular end diastolic volume;peak longitudinal strain during systole of each segment;peak longitudinal strain rate of each segment during shrinkage;systolic longitudinal strain of left and right ventricular walls;global peak systolic longitudinal strain rates of left and right ventricular walls;peak diastolic strain rate of each segment;global longitudinal diastolic strain rate;global sphericity index;24 segment index; | — |
Secondary
| Measure | Time frame |
|---|---|
| left ventricular lateral wall;right ventricular free wall; | — |
Countries
China
Contacts
Public ContactHou Li
Chengdu Women's and Children's Central Hospital
Outcome results
None listed