Rheumatoid Arthritis (RA)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Part I selection criteria: (1) Diagnosed with rheumatoid arthritis on the basis of ACR2010; (2) Aged over 18 years; (3) Inflammatory lesions in at least one small joint (MCP, PIP, wrist); (4) Moderate and severe disease activity; (5) Prepare to receive new treatment options (conventional DMARDs, biological DMARDs, targeted DMARDs), prescribed by a senior and experienced rheumatologist; (6) Maintain a steady dose of the drug for at least 6 weeks before a new course of treatment; (7) Strictly follow the treatment plan and visit schedule; Discontinuation of medication and loss of follow-up will be excluded. 2. Part II inclusion criteria: (1) Diagnosed with rheumatoid arthritis on the basis of ACR2010; (2) Aged over 18 years; (3) CR achieved clinical remission after standard treatment; (4) At least one facet joint had previously developed arthritic lesions; (5) Prepare to stop or reduce the drug.
Exclusion criteria
Exclusion criteria: 1. Unwilling to participate in research or undergo imaging; 2. Unable to complete the study due to physical or mental limitations; 3. Serious adverse events occurred during the study; 4. Complications with other types of arthritis, including osteoarthritis, psoriatic arthritis and gouty arthritis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prognostic area under the curve (AUC); | — |
Secondary
| Measure | Time frame |
|---|---|
| Sensitivity;Specificity;Accuracy; | — |
Countries
China
Contacts
Shenzhen Hospital of Peking University