Postpartum depressive state
Conditions
Interventions
Group A:Esketamine 0.25mg/kg
Group B:Esketamine 0.125mg/kg
Group C:0.9% normal saline
Sponsors
Jiangsu Province Hospital
Eligibility
Sex/Gender
Female
Age
20 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. ASA I or II; 2. Aged range from 20 to 45 years; 3. BMI 18.5~30 kg/m^2; 4. Full-term, singleton, cephalic parturient; 5. Ask for pain relief during labor.
Exclusion criteria
Exclusion criteria: 1. Contraindications of esketamine use (such as hypertension patients); 2. Use sedative hypnosis, analgesia and antidepressants within a week; 3. Patients with a history of drug abuse; 4. History of other mental illnesses; 5. Severe heart, lung, liver and kidney dysfunction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montgomery Depression Rating Scale (MADRS) Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale Score for Pain;Maternal satisfaction; | — |
Countries
China
Contacts
Public ContactHan Chuanbao
Jiangsu Province Hospital
Outcome results
None listed