lumbar degenerative disease
Conditions
Interventions
Group A:Bone marrow enriched bone repair material was used as intervertebral bone graft material in upper vertebral space
Group B:Autologous bone was used as intervertebral bone graft material in upper vertebral space
Sponsors
Department of Orthopedics, the First Affiliated Hospital of Army Military Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with lumbar disc herniation, lumbar spinal stenosis, lumbar spondylolisthesis (I-II degrees) and other degenerative diseases of lumbar, who are ineffective after at least 1 month of conservative treatment, and have surgical indications of lumbar double level fusion; 2. Voluntarily take the test and sign informed consent; 3. No restriction on gender or age; 4. Good understanding and compliance, able to communicate well with researchers and comply with the whole test requirements.
Exclusion criteria
Exclusion criteria: 1. Systemic active infection; 2. Fever or abnormal blood pattern; 3. Suffering from mental illness; 4. Any potential conditions that may affect the effect of fusion implant implantation, such as malignant tumors, congenital malformations, surgical site fractures, and other underlying diseases; 5. Severe osteoporosis; 6. Previous history of severe allergy and rejection of medical materials; 7. The tissue coverage of the patient's surgical site was insufficient; 8. Patients participating in other clinical trials; 9. Other conditions considered inappropriate for inclusion by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Surgical segmental fusion rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgical segmental fusion time;Range of motion of the operative segment;Intraoperative complications;Visual analog pain scores;Oswestry disability index; | — |
Countries
China
Contacts
Public ContactHou Tianyong
Outcome results
None listed