recurrent implantation failure (RIF) and endometriosis (EMs)
Conditions
Interventions
Group 1:intrauterine perfusion of platelet-rich plasma
Group 2:intrauterine perfusion of HCG
Sponsors
The Second People's Hospital of Shenzhen
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 20-40 years. 2. Patients with RIF (defined as failure of implantation in three consecutive embryo transfers of good-quality embryos, fresh or thawed, from IVF). 3. Patients with endometriosis. 4. Patients with reproductive requirements, voluntarily participate in this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Unilateral or bilateral hydrosalpinx or hydrocele; 2. Organic lesions of uterus and uterine cavity (endometrial polyps) and uterine adhesion, endometrial tuberculosis; 3. It is not suitable for the woman to get pregnant or the pregnancy will cause the aggravation of the original disease, which is life-threatening in severe cases, such as serious heart disease, nephritis, hepatitis, etc.; 4. Severe hypoplasia or deformity of the female genitalia; Have an acute infection or sexually transmitted disease; Suffering from a serious genetic, physical or psychiatric disorder; 5. Either party has serious bad habits, cognitive impairment, exposure to teratogenic radiation, poisons, drugs, and due to the action period or chromosomal karyotype abnormalities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the implantation rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| the clinical pregnancy rate;the biochemical pregnancy rate;the early miscarriage rate;the ongoing pregnancy rate; | — |
Countries
China
Contacts
Public ContactLi Ying
The Second People's Hospital of Shenzhen
Outcome results
None listed