None listed
Conditions
Interventions
Healthy group 1:Compound polyethylene glycol electrolyte powder
Healthy group 2:Compound polyethylene glycol electrolyte powder + probiotics
Ulcerative colitis group 1:Compound polyethylene glycol electrolyte powder
Ulcerative colitis group 2:Compound polyethylene glycol electrolyte powder + probiotics
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-60 years, no gender limit; 2. For patients with UC who were clearly diagnosed, the diagnostic criteria were referred to the 2018 Consensus Opinion on the Diagnosis and Treatment of Inflammatory Bowel Disease. At the time of the study, the endoscopy was inactive or mild for at least 2 weeks, and the UC disease activity index was < 4(modified Powell-Tuck index); 3. Healthy control: normal routine physical examination, no gastrointestinal symptoms within 1 month; 4. No antibiotics, antacids or probiotics in the past month, no infection in the past 3 months.
Exclusion criteria
Exclusion criteria: 1. Patients who are pregnant or have a pregnancy plan during the trial; 2. Patients who have any doubts about the technology or have a history of other risks; 3. Patients who are terminally ill or likely to die during the study; 4. Patients who participated in other clinical trials three months before enrollment; 5. Patients who had been treated with any other microflora prior to study enrollment; 6. Patients with severe heart, lung, liver and kidney insufficiency; 7. Abnormal lesions or complications were found during colonoscopy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fecal microbiome; | — |
Countries
China
Contacts
Public ContactChen Xi
Outcome results
None listed