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Effect and mechanism of peony seed oil, tea seed oil and soybean oil on risk factors of cardiovascular and metabolic diseases in Chinese healthy people

Effect and mechanism of peony seed oil, tea seed oil and soybean oil on risk factors of cardiovascular and metabolic diseases in Chinese healthy people

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064455
Enrollment
Unknown
Registered
2022-10-09
Start date
2022-10-09
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiometabolic diseases

Interventions

Intervention group 1:Peony seed oil
Intervention group 2:Tea seed oil

Sponsors

Qingdao University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Staff of the general hospital of the people's liberation army; 2. Aged 18-35 years; 3. 18.5 <= body mass index (BMI) < 27.9; 4. Willing to eat the food provided in a full state; 5. Willing to eat only the food provided by the researchers; 6. Willing to eat at least one meal (lunch or dinner) a day under the supervision of the researcher at the intervention site; 7. Willing to maintain baseline fruit intake during the intervention period; 8. Willing to record food intake every day; 9. Willing to accept informed consent.

Exclusion criteria

Exclusion criteria: 1. Systolic blood pressure >= 140 mm Hg or diastolic blood pressure >= 90 mm Hg; 2. Total cholesterol (TC) >= 6.19 mmol / L; 3. Low density lipoprotein cholesterol (LDL-C) >= 4.12 mmol / L; 4. Triglyceride (tag) >= 2.25 mmol / L; 5. Fasting blood glucose >= 6.1 mmol / L; 6. In the past year, your weight has changed by more than 10% of your own weight; 7. Daily energy intake is too high or too low compared with the recommended intake; 8. Unwilling to adjust dietary habits for the experiment or having special dietary requirements; 9. In the process of volunteer recruitment, they showed poor compliance or could not complete food records and questionnaires well; 10. Eating disorder or mental or time arrangement may affect the test; 11. History of cardiovascular disease, diabetes and cancer; 12. Have a history of mental illness; 13. Have endocrine, lung or blood diseases; 14. Suffering from gastrointestinal diseases; 15. Abnormal liver and kidney function; 16. Suffering from other diseases that may affect volunteers' compliance with the test regulations; 17. Currently taking supplements or drugs that may affect glucose and lipid metabolism; 18. Smoking or drinking >= 1 time / week; 19. Currently or about to be pregnant or breastfeeding.

Design outcomes

Primary

MeasureTime frame
Blood count indicators;Erythrocyte membrane fatty acid profile;Intestinal flora;Fecal metabolomics;Urine metabolomics;

Countries

China

Contacts

Public ContactShi Runjia, Li Duo

Qingdao University

2120094412@qq.com+86 17664055335

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026