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Evaluation of therapeutic effect of Buqi Yangxue Recipe on anterior ischemic optic neuropathy by multimodal imaging

Evaluation of multimodal imaging in the treatment of anterior ischemic optic neuropathy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064452
Enrollment
Unknown
Registered
2022-10-09
Start date
2022-10-08
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non arteritic anterior ischemic optic neuropathy

Interventions

Intervention group:Buqi Yangxue Recipe + Prednisone

Sponsors

Capital Medical University, Beijing Friendship Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Willing to sign informed consent; 2. Aged >=18 years; 3. Within 2 weeks to 1 month after diagnosis of NAION; 4. In screening and baseline, BCVA score must be in the range of 80 to 40 letters (excluding 80 and 40 letters), visual impairment is mainly caused by NIAON, not other causes; 5. Ability and willingness to comply with all scheduled follow-up and evaluation; 6. Clear dioptric media and sufficient pupil dilation, allowing high-quality OCT and OCTA imaging.

Exclusion criteria

Exclusion criteria: 1. Pregnancy or lactation. 2. Other conditions identified by the investigator that would cause serious harm to the subject once the experimental treatment began. 3. Concurrent participation in another medical survey or trial. 4. There are contraindications for MRI and other imaging examinations. 5. MRI examination revealed other eye lesions affecting visual function.

Design outcomes

Primary

MeasureTime frame
The blood flow of optic nerve;

Secondary

MeasureTime frame
Visual accurity;Visual field;Thickness of nerve fiber layer;

Countries

China

Contacts

Public ContactLi Hongyang

Capital Medical University, Beijing Friendship Hospital

faraway_sweet@163.com+86 13301333869

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026