prostate cancer
Conditions
Interventions
Gold Standard:68Ga-PSMA
Index test:FXN001
Sponsors
The Affiliated Hospital of Southwest Medical University
Eligibility
Sex/Gender
Male
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. The male aged >= 18 years, with confirmed mCRPC; 2. Patients with expected survival >= 6 months; with ECOG score of 0, 1, or 2; 3. At least 1 metastatic lesion (on CT or whole-body bone imaging); 4. Patients whose blood routine and liver and kidney function meet the following criteria: blood routine: WBC >= 4.0 x 10^9/L or neutrophil >= 1.5 x 10^9/L, PLT >= 100 x 10^9 / L, Hb >= 90g / L; PT or APTT <= 1.5 ULN; liver and kidney function: T-Bil <= 1.5 ULT (upper limit of normal value), ALT / AST <= 2.5 ULN or <= 5 ULT (liver metastasis patients), ALP <= 2.5 ULN (if there is bone metastasis or liver metastasis, ALP <= 4.5 ULN), bun <= 1.5 ULT, SCR <= 1.5 ULT; 5. Patients with at least one measurable target lesion according to recist 1.1; 6. Men should agree to take contraceptive measures during the study period and within 6 months after the end of the study period; 7. Patients who can understand and voluntarily sign informed consent and have good compliance.
Exclusion criteria
Exclusion criteria: 1. Can not lie flat for half an hour; 2. Suffering from claustrophobia or other mental illness; 3. Conditions deemed unsuitable for participation by other researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Tumor / non-tumor tissue ratio(T/NT);Maximum standardized uptake value; | — |
Countries
China
Contacts
Public ContactChen Yue
The Affiliated Hospital of Southwest Medical University
Outcome results
None listed