The effect and mechanism of glucose variability on cerebrovascular complications of diabetes mellitus: a multimodal magnetic resonance study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200064431

Enrollment

Unknown

Registered

2022-10-07

Start date

2022-10-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebrovascular complications of diabetes mellitus

Interventions

Blood glucose fluctuations(+) group:None

Blood glucose fluctuations(-) group:None

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Diabetic patients with intracranial atherosclerosis and vascular stenosis greater than 30%.

Exclusion criteria

Exclusion criteria: 1. Rheumatic mitral valve disease; 2. Atrial fibrillation; 3. Vulnerable plaque or severe stenosis in the carotid artery; 4, Takayarteritis, rheumatoid and other immune diseases; 5. Renal insufficiency; 6. Intracranial arterial vascular interventional therapy; 7. Have contraindications for MRI examination, such as cardiac pacemaker implantation, cochlear implant, etc., or have claustrophobia.

Design outcomes

Primary

Measure	Time frame
Location and area of new cerebral infarction;An increase in the area or number of demyelinating lesions in the white matter;New symptoms of TIA;New symptoms of cerebral infarction;	—

Secondary

Measure	Time frame
Myocardial ischemia or infarction;	—

Countries

China

Contacts

Public ContactSong Yan

Beijing Hospital

firesong@sina.com+86 18610566272

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026