refractory upper gastrointestinal fistula
Conditions
Interventions
Upper gastrointestinal fistula group:Autologous platelet-rich plasma endoscopic injection
Sponsors
Jiangsu Province Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients aged 18-80 years who have been diagnosed with refractory upper gastrointestinal fistula: 1. No improvement after 3 months of fasting and nutritional support; 2. Patients who cannot tolerate surgical repair or whose repair is ineffective or who refuse surgery; 3. Patients unable to heal after endoscopic treatment; 4. Lack of effective treatment options.
Exclusion criteria
Exclusion criteria: 1. Coagulation dysfunction and bleeding disorders; 2. Serious cardiopulmonary diseases; 3. Cannot tolerate anesthesia; 4. In a state of pregnancy; 5. Acute stage of stroke; 6. Mental illness; 7. Patients who are unable to cooperate with treatment and follow-up; 8. History of postoperative radiotherapy and chemotherapy for esophageal cancer in the past two months; 9. Hb 2cm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete blocking rate of fistula;Granulation coverage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fistula healing rate;Fistula healing time;Incidence of adverse events;Weight changes;Quality of life score; | — |
Countries
China
Contacts
Public ContactZhang Guoxin
Jiangsu Province Hospital (First Affiliated Hospital of Nanjing Medical University)
Outcome results
None listed