Canceled by the investigator. Dezocine can improve the safety and comfort of patients in extubation after general anesthesia: A prospective and randomized controlled study

Dezocine can improve the safety and comfort of patients in extubation after general anesthesia: A prospective and randomized controlled study

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200064393

Enrollment

Unknown

Registered

2022-10-06

Start date

2022-10-06

Completion date

Unknown

Last updated

2023-06-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endotracheal intubation under general anesthesia

Interventions

Group D:dezocine

Group C:normal saline

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult (older than 18 years), ASA1-2, tracheal intubation under general anesthesia

Exclusion criteria

Exclusion criteria: Exclusion criteria included history of heart disease and other internal diseases, abnormal liver or kidney function, hyperthyroidism, history of sedation, hypnosis, drug abuse, contraindications to dezocine use, high airway stress response, and assessment of difficulty in tracheal intubation.

Design outcomes

Primary

Measure	Time frame
numbers of Cough and scores of Cough;	—

Secondary

Measure	Time frame
Hemodynamic and respiratory indicators monitoring: Invasive arterial blood pressure, heart rate and oxygen saturation;Analgesia and sedation scores: V AS score and Ramsay;the duration of time from anaesthetic withdrawal to extubation;Adverse reaction monitoring: The incidence of nausea, dizziness and respiratory depression;	—

Countries

China

Contacts

Public ContactLan Zhang

Sichuan Orthopedic Hospital

1074575980@qq.com18058631145

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026