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Comparison of continuous infusion of two doses of mivacurium during laryngeal microsurgery under general anesthesia

Comparison of continuous infusion of two doses of mivacurium during laryngeal microsurgery under general anesthesia:a prospective, randomized, controlled, double-blind clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064373
Enrollment
Unknown
Registered
2022-10-05
Start date
2022-10-16
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laryngeal microsurgery

Interventions

treatment group:mivacurium0.3mg/kg·h
control group :mivacurium0.5mg/kg·h

Sponsors

Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Patients scheduled for elective laryngeal microsurgery, aged 18-65 years, BMI (body mass index) between 18-30 kg/m^2, ASA: class I-III, agreed to participate in this study and signed an informed consent form preoperatively.

Exclusion criteria

Exclusion criteria: Patients allergic to mivacurium, those with severe liver and kidney dysfunction, those with predictable difficult airways, those with abnormal plasma cholinesterase, those with neuromuscular disease and asthma.

Design outcomes

Primary

MeasureTime frame
extubation time;—

Secondary

MeasureTime frame
recovery indexes;Cooper's scores;Cormack-Lehane grades;surgical condition grades;TOF ratio in the post anesthesia care unit (PACU);Tidal volume after extubation;SpO2 in the post anesthesia care unit (PACU);T1 in the PACU;mivacurium consumption;—

Countries

China

Contacts

Public ContactGuyan Wang
guyanwang2006@163.com+86 13910985139

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026