Infertility
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Participants are eligible to be included in the study only if all the following criteria apply: 1. POSEIDON group I who underwent the second cycle following GnRH antagonist protocol POSEIDON group I: Patients= 5, AMH >= 1.2 ng/mL) and with an unexpected poor or suboptimal ovarian response with the retrieval of zero to nine oocytes 2. Age 20-35 years old in the second IVF cycle; 3. 18<BMI<26 kg/m^2; 4. GnRH antagonist protocol with rFSH stimulation in the first cycle; 5. Without ART contradictions.
Exclusion criteria
Exclusion criteria: Participants are excluded from the study if any of the following criteria apply: 1. Patients who required starting dose or dose adjustments >300 IU in the first cycle; patients who employed average dose <150IU/d during stimulation with rFSH in their previous cycle; 2. Uterine disorders (intrauterine adhesions, uterine fibroids, endometritis, etc.); 3. Patients with endocrine and metabolic disease diseases (diabetes mellitus, hypogonadotropic amenorrhea, genital system tumors, hyperprolactinemia, chromosomal disorders, etc.); 4. Patients with other pelvic and abdominal diseases (III-IV endometriosis, inflammatory, autoimmune, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Retrieved oocytes number; | — |
Countries
China
Contacts
West China Second Hospital, Sichuan University