COVID-19
Conditions
Interventions
COVID-19 patients after discharge:none
normal healthy controls:none
Sponsors
Yueyang Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Discharged patients with COVID-19: (1) Between the ages of 18 and 70, both sexes; (2) Infected with COVID-19 locally in 2022 and discharged after treatment and the nucleic acid test conversed to negative; (3) Volunteer to participate in this study and sign the informed consent form. 2. Normal healthy controls: (1) Aged 18-70 years, matched with the age and gender of COVID-19 discharged patients; (2) Have not been infected with novel coronavirus; (3) Voluntarily participate in this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Having a pacemaker; 2. Skin damage, ulceration and other conditions that disturb the examination sites of skin sympathetic response(non-dominant side palm, plantar); 3. A history of heavy drinking, diabetes and other risk factors affecting peripheral nerves; 4. Previous autonomic nerve dysfunction; 5. Patients with primary pulmonary diseases, such as lung tumors, severe pulmonary interstitial fibrosis, chronic obstructive pulmonary disease, etc.; 6. Severe primary diseases of the heart, brain, liver, gastrointestinal tract, kidney, blood, and endocrine systems; 7. Previously diagnosed with anxiety disorder, depression, and other mental diseases; 8. Previous sleep disorders; (9) The subject has uncontrolled concurrent diseases and other conditions that the researchers consider nnot suitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| sympathetic skin response;Hamilton Depression Scale;Pittsburgh sleep quality index; | — |
Secondary
| Measure | Time frame |
|---|---|
| functional near-infrared spectroscopy;Borg dyspnea score;30-second sit-stand test;2-minute step test;Classification of cardiac function by New York Heart Association;manual muscle test; | — |
Countries
China
Contacts
Public ContactJiayin Ma
Yueyang Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed