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A comparative study of esketamine and dexmedetomidine on postoperative emotion in breast cancer patients

A comparative study of esketamine and dexmedetomidine on postoperative emotion in breast cancer patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064341
Enrollment
Unknown
Registered
2022-10-03
Start date
2022-10-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast cancer

Interventions

esketamine group:0.5mg/kg esketamine i.v
Dexmedetomidine group:Pump 0.5µg/(kg*h)dexmedetomidine
Esketamine and dexmedetomidine group:0.5mg/kg esketamine i.v , pump 0.5µg/(kg*h)dexmedetomidine
control group:Nil

Sponsors

THE FIRST AFFILIATED HOSPITAL of GUANGXI MEDICAL UNIVERSITY
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-65 years; 2. American Society of Anesthesiologists (ASA) grading ?-?; 3. The patient is tolerant to ketamine and dexmedetomidine and intends to have breast cancer surgery under general anesthesia; 4. All patients signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with pre-operative cognitive dysfunction; 2. Complicated with severe liver and kidney dysfunction; 3. Previous cardiovascular and cerebrovascular diseases or central nervous system diseases; 4. There are serious hearing, vision, speech, and other reasons for the inability to communicate normally.

Design outcomes

Primary

MeasureTime frame
PHQ-9 scale;GAD-7 scale;—

Countries

China

Contacts

Public ContactXie Yubo

THE FIRST AFFILIATED HOSPITAL of GUANGXI MEDICAL UNIVERSITY

xybdoctor@163.com+86 771 5356250

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026