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Effects of inadequate ventilation on cerebral blood flow, hemodynamics, and heart rate variability during endotracheal intubation

Effects of inadequate ventilation on cerebral blood flow, hemodynamics, and heart rate variability during endotracheal intubation: a prospective cohort study

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200064295
Enrollment
Unknown
Registered
2022-10-02
Start date
2022-10-15
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mask ventilation difficulty

Interventions

Mask ventilation difficulty group:None
Control group:None

Sponsors

Lianyungang Hospital affiliated to Jiangsu University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Elective surgery under general anesthesia. 2. Regardless of gender,aged 18 years to 65 years. 3. American Society of Anesthesiologists (ASA) physical status 1 or 2.

Exclusion criteria

Exclusion criteria: We used the following criteria to exclude participants: 1. cardiovascular disease, peripheral vascular disease, cerebrovascular disease, severe hepatic and renal dysfunction, endocrine system disease, respiratory system disease, mental or central nervous system disease disorders. 2. None of the patients were allergic to the drugs used in the study or were taking drugs that affect cardiovascular function. 3. Refused to participate in this experiment.

Design outcomes

Primary

MeasureTime frame
Systolic blood pressure;

Secondary

MeasureTime frame
Diastolic blood pressure;Systolic velocity;Diastolic velocity;Mean velocity;Pulsitility index;Resistance index;Heart rate;Mean arterial pressure;The ratio of systolic to diastolic velocity;Heart rate variability;Multiple linear regression model;

Countries

China

Contacts

Public ContactJunlong Zhang

Lianyungang Hospital affiliated to Jiangsu University

zjlddqzyw@126.com+86 15715139688

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026