obesity
Conditions
Interventions
Sunflower intervention group :Sunflower products
CCFM1062 Group:Bifidobacterium adolescentis CCFM1062
Competitive product group :Bifidobacterium animalis B420
placebo :placebo
Sponsors
Jiangnan University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ? 18 years old = age = 65 years old, male or female; ? BMI=26.0kg/m2 (refer to the Guidelines for the Prevention and Control of Overweight and Obesity in Chinese Adults); ? Stable body weight (±5 kg) within 6 months; ? Good diet, no high-fat and high-salt diet, no overeating or retaliatory eating, and no large-scale dieting; ? Make sure not to consume other weight loss drugs during this experiment; be willing not to consume other probiotics or fermented dairy products during this study, but still stick to previous eating habits; ? Good compliance, able to abide by the requirements of clinical trials; ? The subject or guardian has signed the informed consent; ? The patients fill in the written informed consent form, the International Physical Activity Scale and the Dietary Structure Questionnaire, and promise to cooperate with the research throughout the trial period.
Exclusion criteria
Exclusion criteria: ? Regular intake of antibiotics and corticosteroids, and vitamins within the past 6 months; ? Abuse of narcotics, psychotropic substances and cigarettes in the past 6 months; ? Rapid weight loss or gain in the past 6 months, malnutrition in daily food intake, total parenteral nutrition and protein malnutrition; ? During the study period or within the past 3 months, supplement nutrients such as probiotics and various minerals at least twice a week; ? Pregnant or lactating women, or planning to become pregnant in the next 6 months; ? No plan to lose weight or gain weight in the next 6 months; ? Allergy or intolerance to the ingredients of the test probiotic product; ? Poor patient compliance and poor possibility of follow-up;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| BMI; | — |
Secondary
| Measure | Time frame |
|---|---|
| body fat percentage;Waist circumference;subcutaneous fat thickness;blood;Levels of liver; Analysis of gut microbiota;Analysis of metabolites;diet structure survey; International Physical Activity Scale; | — |
Countries
China
Contacts
Public ContactFeng Zhang
Outcome results
None listed