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Immediate versus delayed frozen embryo transfer in patients using natural cycle following freeze-all strategy: a randomised controlled trial

Immediate versus delayed frozen embryo transfer in patients using natural cycle following freeze-all strategy: a randomised controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064273
Enrollment
Unknown
Registered
2022-10-01
Start date
2022-10-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

Immediate group:Immediate FET in the first cycle following freeze-all strategy
Delayed group:Delay FET in at least the second cycle following freeze-all strategy

Sponsors

Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Undergoing GnRH antagonist protocol 2. Women aged <= 40 years at the time of IVF/ICSI treatment 3. At least one frozen cleavage stage embryo or blastocyst 4. Freeze-all strategy 5. Regular menstrual cycle (21–35 days) and using natural cycle to prepare the endometrium

Exclusion criteria

Exclusion criteria: 1. Uterine malformation; 2. BMI>= 30 kg/m2; 3. Cycle of donor or vitrified oocytes ; 4. Preimplantation genetic testing treatment; 5. Severe ovarian hyperstimulation syndrome during IVF/ICSI treatment ; 6. Presence of untreated hydrosalpinx, intrauterine adhesion, submucosal fibroid, or endometrial polyp.

Design outcomes

Primary

MeasureTime frame
Ongoing pregnancy rate;

Secondary

MeasureTime frame
Cancelled cycle rate;Day of ovulation calculated from the first day of menstrual bleeding;Time-to-pregnancy from the start of ovarian stimulation in the fresh cycle to the date of ongoing pregnancy;Implantation rate;Clinical pregnancy;Early abortion rate;

Countries

China

Contacts

Public ContactXiufeng Ling

Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital

lingxiufeng_njfy@163.com+86 13505173488

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026