Infertility
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Undergoing GnRH antagonist protocol 2. Women aged <= 40 years at the time of IVF/ICSI treatment 3. At least one frozen cleavage stage embryo or blastocyst 4. Freeze-all strategy 5. Regular menstrual cycle (21–35 days) and using natural cycle to prepare the endometrium
Exclusion criteria
Exclusion criteria: 1. Uterine malformation; 2. BMI>= 30 kg/m2; 3. Cycle of donor or vitrified oocytes ; 4. Preimplantation genetic testing treatment; 5. Severe ovarian hyperstimulation syndrome during IVF/ICSI treatment ; 6. Presence of untreated hydrosalpinx, intrauterine adhesion, submucosal fibroid, or endometrial polyp.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ongoing pregnancy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cancelled cycle rate;Day of ovulation calculated from the first day of menstrual bleeding;Time-to-pregnancy from the start of ovarian stimulation in the fresh cycle to the date of ongoing pregnancy;Implantation rate;Clinical pregnancy;Early abortion rate; | — |
Countries
China
Contacts
Women’s Hospital of Nanjing Medical University, Nanjing Maternity and Child Health Care Hospital