Patients on mechanical ventilation during cardiopulmonary bypass
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years old; 2. Open heart surgery under cardiopulmonary bypass (coronary artery bypass grafting, heart valve replacement, type A aortic dissection, tetralogy of fallot, atrial myxoma, etc.); 3. The estimated time of ventilator-assisted ventilation through airway intubation was >= 48 hours.
Exclusion criteria
Exclusion criteria: 1. mean arterial pressure < 60mmHg (under small and medium doses of vasoactive drugs) or increasing doses of vasoactive drugs in the past 2 hours; 2. tracheotomy; 3. Have a history of moderate to severe COPD or emphysema; 4. pulmonary bullae; 5. pneumothorax. 6. Intracranial hypertension; 7. Postoperative adjuvant therapy with ECMO or IABP; 8. Patients with severe pulmonary hypertension; 9. Refused to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of atelectasis; | — |
Countries
China
Contacts
The First Affilated Hospital of Wannan Medical College