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The application effect of personalized positive end respiratory pressure in preventing atelectasis in patients after cardiopulmonary bypass

The application effect of personalized positive end respiratory pressure in preventing atelectasis in patients after cardiopulmonary bypass

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064272
Enrollment
Unknown
Registered
2022-10-01
Start date
2022-10-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients on mechanical ventilation during cardiopulmonary bypass

Interventions

experimental group:Set PEEP according to best compliance

Sponsors

The First Affilated Hospital of Wannan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years old; 2. Open heart surgery under cardiopulmonary bypass (coronary artery bypass grafting, heart valve replacement, type A aortic dissection, tetralogy of fallot, atrial myxoma, etc.); 3. The estimated time of ventilator-assisted ventilation through airway intubation was >= 48 hours.

Exclusion criteria

Exclusion criteria: 1. mean arterial pressure < 60mmHg (under small and medium doses of vasoactive drugs) or increasing doses of vasoactive drugs in the past 2 hours; 2. tracheotomy; 3. Have a history of moderate to severe COPD or emphysema; 4. pulmonary bullae; 5. pneumothorax. 6. Intracranial hypertension; 7. Postoperative adjuvant therapy with ECMO or IABP; 8. Patients with severe pulmonary hypertension; 9. Refused to participate in the study.

Design outcomes

Primary

MeasureTime frame
Incidence of atelectasis;

Countries

China

Contacts

Public ContactPeng Zhang

The First Affilated Hospital of Wannan Medical College

yjsrtzp@126.com+86 18055368287

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026