Polycythemia Vera
Conditions
Interventions
Sponsors
The Forth Affiliated Hospital Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Age = 18 years old 2. Patients diagnosed with polycythemia vera (PV) according to WHO (2016) 3. According to the age (>= 67 years old is 5 points, 57~66 years old is 2 points), wbc>15*10^9/l (1 point), venous thrombosis (1 point), after the prognosis evaluation, the score = 1 point, belonging to the medium-risk group or high-risk group; 4 .Expected survival time > 24 weeks;
Exclusion criteria
Exclusion criteria: 1. Patients with incomplete follow-up data or lost follow-up during follow-up; 2. The patients who had not fully recovered from surgery within 4 weeks before screening; 3. Patients with grade III or above congestive heart failure (NYHA grade), uncontrollable or unstable angina pectoris or myocardial infarction, cerebrovascular accident or pulmonary embolism within 6 months before screening; 4. Patients with arrhythmia requiring treatment or QTc interval (qtcb) >480ms during screening; 5. Bacterial, viral, parasitic or fungal infections requiring treatment with any clinical symptoms at the time of screening; 6. Concomitant with other serious diseases, or considered unsuitable for use by the investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete remission;Partial remission;Not responsive;Progressive disease;Event free survival;Safety; | — |
Countries
China
Contacts
Public ContactJian Huang
The Forth Affiliated Hospital Zhejiang University School of Medicine
Outcome results
None listed