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Screening of biomarkers of sepsis cardiomyopathy based on metabolomics technology

Screening of biomarkers of sepsis cardiomyopathy based on metabolomics technology

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200064245
Enrollment
Unknown
Registered
2022-10-01
Start date
2022-10-01
Completion date
Unknown
Last updated
2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

septic cardiomyopathy

Interventions

septic cardiomyopathy group:None
sepsis without cardiomyopathy group :None

Sponsors

Hunan Provincial People's Hospital, The first-affiliated hospital of Hunan norma
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The diagnostic criteria for sepsis are based on the "Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016" published by JAMA, with clear infection site and infection symptoms, sequential organ dysfunction (SOFA) score >= 2 points or qSOFA Score >= 2 points. Inclusion criteria for septic cardiomyopathy, on the basis of meeting the diagnosis of sepsis, also meet the following criteria: creatine kinase (CK-MB) >= 2 times normal high value; and/or troponin I (cTnI) >Upper limit of normal; and/or echocardiography suggestive of systolic or diastolic dysfunction.

Exclusion criteria

Exclusion criteria: 1. A history of chronic cardiac insufficiency, dilated cardiac hypertrophy, obstructive cardiomyopathy or valvular heart disease; 2. Atrial fibrillation (interfering with echocardiography); 3. Age <18 years old; 4. Pregnancy.

Design outcomes

Primary

MeasureTime frame
Plasma metabolic profile analysis;

Countries

China

Contacts

Public ContactYan Cao

Hu'nan Provincial People's Hospital, The first-affiliated hospital of Hunan normal university

vivian.yancao@foxmail.com+86 15116485862

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026