The effect of linaclotide combined with polyethylene glycol electrolytes powder on bowel preparation for colonoscopy

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200064244

Enrollment

Unknown

Registered

2022-10-01

Start date

2022-10-01

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bowel preparation

Interventions

1 Linaclotide+2L PEG:1 Linaclotide+2L PEG

3L PEG:3L PEG

2 Linaclotide+1L PEG :2 Linaclotide+1L PEG

Eligibility

Sex/Gender

All

Age

No minimum to 90 Years

Inclusion criteria

Inclusion criteria: 1. Aged <= 90 years; 2. Informed consent; 3. Complete the research according to the protocol.

Exclusion criteria

Exclusion criteria: 1. Severe heart failure (NYC grade III or IV); 2. Myocardial infarction within 6 months; 3. Chronic kidney disease (CKD 4 or 5); 4. Decompensated cirrhosis or liver failure; 5. Pregnant or lactating women; 6. Intestinal obstruction or perforation; 7. Using of gastrointestinal motility drugs, laxatives, antidiarrheal drugs, antibiotics, probiotics, opioids and NSAIDs within 2 weeks; 8. Severe lower gastrointestinal bleeding; 9. Allergic to linaclotide or polyethylene glycol electrolytes powder; 10. Mental illness and unable to cooperate with the research; 11. Refuse to sign informed consent.

Design outcomes

Primary

Measure	Time frame
First defecation time;Defecation times;Adverse reaction;Bowel preparation cleanliness score (Boston score);Time to ileocecal junction;Lesion detection rate;	—

Countries

China

Contacts

Public ContactChuan Wang

Chongqing General Hospital

Dr_wangchuan@outlook.com+86 13637933810

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026