Nasopharyngeal Carcinoma
Conditions
Interventions
single arm:Pseudomembranous Dissection
Sponsors
Jiangxi Cancer Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Nasopharyngeal non-keratinizing carcinoma without distant metastases was initially treated. 2. Suitable for radical radiotherapy, and complete radical radiotherapy. 3. Pseudomembrane reaction occurred in the nasopharyngeal mucosa during and after radiotherapy. 4. Karnofsky score >= 70 points. 5. Expected survival more than 1 year. 6. Induction chemotherapy + concurrent chemotherapy + adjuvant chemotherapy or concurrent chemoradiotherapy + adjuvant chemotherapy or radiotherapy alone are allowed. 7. The patients were able to comply with the study and follow-up procedures, and the patients signed a formal informed consent to demonstrate that they understood that the study was in compliance with the hospital's policy and ethical requirements.
Exclusion criteria
Exclusion criteria: 1. Recurrent radiotherapy for recurrent nasopharyngeal carcinoma; 2. Uncompleted radical radiotherapy; 3. Nasal endoscopic intolerance; 4. Nasal atresia, endoscopic failure; 5. Coagulation dysfunction; 6. Hereditary bleeding constitution; 7. Patients undergoing anticoagulation therapy; 8. Platelets<= 50×10^9/L.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1-year nasopharyngeal necrosis rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Necrosis-Free Survival;Overall Survival;Progression-Free Survival;Time of Pseudomembrane Duration; | — |
Countries
China
Contacts
Public ContactPeng Shiyi
Jiangxi Cancer Hospital
Outcome results
None listed