Post-stroke cognitive impairment
Conditions
Interventions
Group B :Intermittent Theta Burst Transcranial Magnetic Stimulation
Sponsors
Zhujiang Hospital of Southern Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for stroke as defined by the 4th National Academic Conference on Cerebrovascular Diseases in 1995 and confirmed by CT or MRI of the head. 2. First attack, unilateral lesion, duration of disease between 3-12 months. 3. Right-handedness. 4. Aged 18-80 years. 5. Cognitive impairment (total score <= 24) as assessed by the Montreal cognitive assessment (MoCA). 6. No severe aphasia and able to complete cognitive tests. 7. Stable vital signs and no progression of neurological symptoms 8. Normal cognitive function prior to stroke. 9. Voluntary participation and signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. History of previous stroke. 2. CT/MRI confirmed complete damage to the left prefrontal cortex. 3. Bilateral brain lesions. 4. Previous transcranial surgery or current presence of a cranial defect. 5. Ongoing use of antidepressants or neuroleptics. 6. Metal implants or pacemakers in close proximity to the treatment site. 7. Previous other brain disorders such as brain tumours, traumatic brain injury, seizures, etc. 8. History of malignancy. 9. Failure of vital organs. 10. Any neuropsychiatric comorbidities and affective disorders that may affect the test results. 11. Any other factors that may affect cognitive assessment and treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Montreal Cognitive Assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| rest electroencephalogram;Auditory Verb Learning Test;Symbol Digit Modalities Test;Digital Span Test; | — |
Countries
China
Contacts
Public ContactKang-lin Wang
Zhujiang Hospital of Southern Medical University
Outcome results
None listed