Acute postoperative pain
Conditions
Interventions
0.25% ropivacaine group: intraperitoneal infiltration with 0.25% ropivacaine
0.5% ropivacaine group : intraperitoneal infiltration with 0.5% ropivacaine
control group:intraperitoneal infiltration with0.9% normal saline
Sponsors
Beijing Shijitan Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing elective laparoscopic sleeve gastrectomy; 2. Age 18-60 years, both sexes; 3. BMI>= 28 kg/m2 ; 4. American Society of Anesthesiologists (ASA) Class I-III; 5. Patients and their family members agreed and signed informed consent
Exclusion criteria
Exclusion criteria: 1. Patients with myocardial infarction, heart failure and cerebral infarction occurred in the past 1 month; 2. NYHA class III or above, severe valvular disease, ventricular arrhythmias and block; 3. Severe liver (Child-Pugh liver function grade C), renal insufficiency (serum creatinine level > 442µmol/L, or renal replacement therapy); 4. Severe anemia (Hb1.5) or hematological diseases; 6. Other types of bariatric surgery; 7. patients with allergic history to local anesthesia; 8. patients with communication and communication disorders; 9. Patients aged >65 years and <18 years; 10. Patients with ASA grade III or higher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NRS pain score at 6 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain score at 1h, 2h, 12h, 24h and 48h after operation;Sleep score (NRS) 1 and 2 days after surgery;The use of postoperative analgesic pump, and the dosage of remedial analgesic drugs;First time out of bed, first exhaust time, hospital stay;Postoperative adverse events; | — |
Countries
China
Contacts
Public ContactPengfei Liu
Beijing Shijitan Hospital, Capital Medical University
Outcome results
None listed