Epidural-related maternal fever
Conditions
Interventions
Sponsors
Women's Hospital of Nanjing Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. ASA status I-II; 2. Age 18-40 years old 3. Body mass index = 37 weeks 5. Singleton, cephalic, primipara 6. Requires epidural analgesia, and the cervical dilatation is less than or equal to 2cm 7. No contraindications to epidural anesthesia 8. No pregnancy-related diseases such as gestational hypertension, gestational diabetes mellitus 9. No infectious diseases (such as hepatitis B, or syphilis) 10. No abnormal fetal heart rate monitoring before labor analgesia (fetal heart rate range 110-160bpm) 11. The initial body temperature is normal.
Exclusion criteria
Exclusion criteria: 1. The cervical dilatation is >= 3cm when labor analgesia is required 2. Contraindications to spinal anesthesia (eg: abnormal coagulation function, infection at the puncture site) 3. Those who have difficulty in epidural puncture (eg, scoliosis, ankylosing spondylitis) 4. Those who are known to be allergic to the study drug or other drugs used in the study 5. Those who use opioids or other sedative and analgesic drugs within one week, those who use magnesium sulfate and antipyretic drugs 6. Those with a history of drug abuse 7. Patients with sleep apnea syndrome 8. Those with severe heart, lung, liver, and kidney dysfunction 9. Those with symptoms of infection (such as a cold) 10. The amniotic sac has been broken when entering the delivery room
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of epidural-related interpartum fever; | — |
Secondary
| Measure | Time frame |
|---|---|
| Maternal body temperature after initiation of epidural labor analgesia;Hourly opioid consumption;Total dosage of analgesic pump after delivery;The duration of amniotic sac rupture;The way of membrane rupture;The number of vaginal digital examination;Labor outcome;Neonatal outcome; | — |
Countries
China
Contacts
Public ContactShqin Xu
Women's Hospital of Nanjing Medical University
Outcome results
None listed