Microbiological evaluation and the prognosis of apical root canal system in immature teeth

Microbiological evaluation of root canal system in immature teeth during pulp revascularization

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200064203

Enrollment

Unknown

Registered

2022-09-30

Start date

2022-09-30

Completion date

Unknown

Last updated

2023-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endodontic lesions / periapical lesions in immature teeth

Interventions

dens evaginatus group:N/A

dental trauma group:N/A

Eligibility

Sex/Gender

All

Age

7 Years to 20 Years

Inclusion criteria

Inclusion criteria: 1. immature teeth 2. the endodontic or periapical lesions caused by dens evaginatus or dental trauma 3. the teeth have not been treated before 4. those who had not received antibiotic treatment during the previous 3 months 5. those who had not any general disease

Exclusion criteria

Exclusion criteria: 1. mature teeth 2. the endodontic or periapical lesions caused by other reasons, except dens evaginatus or dental trauma 3. the teeth have been treated before 4. those who had received antibiotic treatment during the previous 3 months 5. those who had any general disease

Design outcomes

Primary

Measure	Time frame
16S rRNA bacteria sequencing;the thickness of root canal wall;radiographic root area;radiographic canal area;	—

Secondary

Measure	Time frame
the length of tooth root;	—

Countries

China

Contacts

Public ContactShuli Deng

Affiliated Stomatology Hospital of Zhejiang University

dengshuli@zju.edu.cn+86 13588165567

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026