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Exploring the effect and mechanism of physical therapy on pain and function in patients with knee osteoarthritis based on fNIRS

Exploring the effect and mechanism of physical therapy on pain and function in patients with knee osteoarthritis based on fNIRS

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064175
Enrollment
Unknown
Registered
2022-09-29
Start date
2022-09-29
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

Therapy group:Physical factor therapy and conventional drug therapy
Control group:Conventional drug therapy

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. The subject has knee pain and is diagnosed with knee osteoarthritis (relevant diagnosis certificate from a regular medical institution is required) or KOA is diagnosed according to the diagnosis and treatment guidelines of the Chinese Orthopaedic Association (COA) in 2021. (1) and (any two of (2), (3), (4), (5)): (1) Recurrent knee pain within the past 1 month; (2) Joint space narrowing, subchondral bone sclerosis and (or) cystic degeneration, and osteophyte formation at the joint edge; (3) Aged >= 50 years; (4) Morning stiffness no more than 30 minutes; (5) There is a feeling of bone friction during activities. 2. The sensory sensation of the lower limbs was normal, and there was no open wound around the knee.

Exclusion criteria

Exclusion criteria: 1. Diagnosed with rheumatoid arthritis, gout or severe osteoporosis; 2. History of knee surgery within the past 6 months, with local metal; 3. Suffering from dementia, severe cognitive impairment and other types of mental illness; 4. Those who suffer from heart failure, severe anemia, and stroke, and have a pacemaker installed in their body; 5. Unable to participate in the trial due to other health problems; 6. Unable to sign informed consent or participate in other scientific research projects.

Design outcomes

Primary

MeasureTime frame
Indices such as cerebral hemodynamics based on fNIRS;

Secondary

MeasureTime frame
WOMAC;NRS;

Countries

China

Contacts

Public ContactRan An

West China Hospital, Sichuan University

neuroanr@163.com+86 13488980926

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026