obesity
Conditions
Interventions
placebo group:placebo
Sponsors
China Agricultural University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-65 years; 2. BMI >= 28 kg/m2 or the percentage of total fat reaches more than 25% for men and more than 30% for women; 3. Dyslipidemia: TC >= 5.2 mmol/L or LDL-C >= 3.4 mmol/L or TG >= 1.7 mmol/L or HDL-C < 1.0 mmol/L according to "Guidelines for prevention and treatment of dyslipidemia in Chinese adults (2016 Revision)"; 4. Volunteer to participate in the test and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Suffering from mental disease, gastrointestinal disease, diabetes, heart, liver, kidney, hematopoietic system or immune system and other serious diseases; 2. Currently in pregnancy or lactation; 3. People with allergies; 4. Those who have used probiotics, lipid-lowering drugs, antibiotics, proton pump inhibitors, laxatives, antidiarrheals, antibacterial agents (such as berberine) and hormones within 4 weeks; 5. Those whose blood lipid level reaches high risk level, i.e. LDL-C >= 4.9 mmol/L or TC >= 7.2 mmol/L; 6. Subjects participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body fat percentage;total glyceride;total cholesterol; | — |
Secondary
| Measure | Time frame |
|---|---|
| BMI;Body fat weight;Muscle weight;waist;LDL-C;HDL-C;Inflammatory factor;Intestinal Metabolites;Blood Metabolites;Hipline; | — |
Countries
China
Contacts
Public ContactJingjing He
China Agricultural University
Outcome results
None listed