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The protective effect and potential mechanism of vascular endothelial autophagy on atherosclerosis induced by high fat diet

The protective effect and potential mechanism of vascular endothelial autophagy on atherosclerosis induced by high fat diet

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200064155
Enrollment
Unknown
Registered
2022-09-28
Start date
2022-09-23
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atherosclerosis

Interventions

coronary atherosclerotic heart disease group:none
control group:none

Sponsors

Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with the coronary atherosclerotic heart disease (CAD) who exhibited at least one major coronary artery with a greater than 50% stenosis and patients without clinically significant coronary artery occlusion.

Exclusion criteria

Exclusion criteria: Patients that combined with malignant tumors, endocrine diseases and other autoimmune diseases.

Design outcomes

Primary

MeasureTime frame
apoptosis of endothelial cell;endothelial miR-204-5p expression;endothelial miR-204-5p expression;—

Countries

China

Contacts

Public ContactSun Changhao

Harbin Medical University

tianzhen19951111@163.com18845875776

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026