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Efficacy of endoscopic radiofrequency ablation for severe atrophy of gastric mucosa with moderate to severe intestinal metaplasia

Efficacy of endoscopic radiofrequency ablation for severe atrophy of gastric mucosa with moderate to severe intestinal metaplasia: a single center, single-arm clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064134
Enrollment
Unknown
Registered
2022-09-27
Start date
2022-09-28
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe atrophy of gastric mucosa with moderate to severe intestinal metaplasia

Interventions

experimental group:endoscopic radiofrequency ablation

Sponsors

The First Affiliated Hospital, College of Medicine, Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 20-80 years; 2. Patients with severe atrophy of gastric mucosa with moderate to severe intestinal metaplasia diagnosed by endoscopy, confocal laser microendoscopy and pathological biopsy; 3. Preoperative routine blood test and coagulation function tests were normal.

Exclusion criteria

Exclusion criteria: 1. Long-term oral non-steroidal anti-inflammatory drugs or bleeding tendency; 2. History of severe cardiopulmonary disease or other organ dysfunction; 3. Combined with other organ malignant tumors; 4. Pregnant.

Design outcomes

Primary

MeasureTime frame
Upper gastrointestinal endoscopy and biopsy;—

Secondary

MeasureTime frame
Pepsinogens-I;Pepsinogens-II;Gastrin-17;—

Countries

China

Contacts

Public ContactChaohui Yu

The First Affiliated Hospital, College of Medicine, Zhejiang University

ych623@sina.com13957161659

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026