polycystic ovarian syndrome
Conditions
Interventions
Experimental group:receiving personalized embryo transfer based on endometrial receptivity test
Control group:Receiving conventional embryo transfer
Sponsors
Xiangya Hospital, Central South University
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed with PCOS according to 2003 Rotterdam criteria; 2. Aged 20-35 years; 3. Having 2 or more good-quality frozen embryos; 4. Willing to join the study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Accompany with endometrial diseases, including intrauterine adhesions, endometrial tuberculosis, atypical endometrial hyperplasia, untreated endometrial polyps or endometritis, etc.; 2. Accompany with uterine diseases, including uterine malformation, uterine mediastinum, intramural fibroids compressing the uterine cavity line, etc.; 3. Untreated severe hydrosalpinx; 4. Stage III-IV endometriosis; 5. Accompaned with other diseases that affect embryo implantation, such as prethrombotic state, immune system diseases (systemic lupus erythematosus, Sjgren's syndrome, etc.), malignant tumors, uncontrolled diabetes, hypertension, etc.; 6. Patients with repeated implantation failure, defined as have received 2 or more embryo transfers cycles, transferred 2 high-quality blastocysts or 4 high-quality cleavage-stage embryos without pregnancy; 7. Patients who have undergone ovarian wedge resection or ovarian drilling; 8. Patients who have used androgen inhibitors, contraceptives, etc. in the past 3 months; 9. Patients with recurrent miscarriage, defined as having experienced 3 or more pregnancy losses (including biochemical pregnancy); 10. Other factors that researchers consider unsuitable to participate in this study, such as mental factors, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intrauterine clinical pregnancy rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Biochemical pregnancy rate;Embryo implantation rate;Ongoing clinical pregnancy rate;Live birth rate;Ectopic pregnancy rate;Miscarriage rate;Multiple pregnancy rate; | — |
Countries
China
Contacts
Public ContactLi Yanping
Xiangya Hospital, Central South University
Outcome results
None listed