A multicenter, prospective clinical study of low-dose inhaled indocyanine green-guided intraoperative fluorescence imaging of pulmonary nodules

A multicenter, prospective clinical study evaluating low-dose inhalation indocyanine green-guided precise intraoperative fluorescence imaging of pulmonary nodules

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200064107

Enrollment

Unknown

Registered

2022-09-26

Start date

2022-09-26

Completion date

Unknown

Last updated

2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

Group A:Routine thoracoscopic surgery

Group B:Aerosol inhalation of ICG fluorescence thoracoscopy

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Chest CT showed pulmonary nodules with a diameter of 0.8-2.0 cm within 2 cm of the pleura; 2. Patients who were going to undergo thoracoscopic lung surgery; 3. Aged 18-70 years; 4. Voluntarily participate in this study and sign Informed consent.

Exclusion criteria

Exclusion criteria: 1. Those who are allergic to indocyanine green; 2. Have asthma or atelectasis; 3. Concomitant infectious diseases; 4. Have other factors deemed inappropriate by researchers.

Design outcomes

Primary

Measure	Time frame
Nodule exploration time;	—

Secondary

Measure	Time frame
Enlarge the margin ratio;Fluorescence signal intensity;Fluorescence specificity and sensitivity;Intraoperative discovery of additional nodules;Total operation time;Operative blood loss;Incidence of postoperative complications;	—

Countries

China

Contacts

Public ContactJian Zhou

472373187@qq.com+86 13811765740

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026