Childhood Cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 6-19 years (not including 19) at the time of enrollment; 2. Diagnosis:First diagnosis of malignant neoplasm or in first and continuous remission at the time of enrollment, without chronic graft versus host disease (cGVHD) for patients with previous HSCT; 3. Prior therapy modalities: Curative cancer treatment must have included chemotherapy and/or radiation and/or surgery and/or HSCT; 4. Timing: All cancer treatment must have been completed at least 12 calendar months prior to enrollment; no anti-rejection drugs for patients with previous HSCT at least 12 calendar months; 5. Performance Status:Ambulatory and no known medical contraindications to increasing physical activity.
Exclusion criteria
Exclusion criteria: 1. Down's syndrome, or major congenital or hereditary disease with organ dysfunction; 2. Known underlying congenital immunodeficiency or metabolic disease; 3. Congenital heart disease with cardiac insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anthropometrics information (Weight, height and arm circumference) and blood pressure;Cardiopulmonary exercise test;Respiratory muscle and lung function tests; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood glucose;serum lipid;CRP;C-Peptide;Thyroid function test;BNP/NT-proBNP;cTnI; | — |
Countries
China
Contacts
Shanghai Jiaotong University School of Medicine Affiliated Shanghai Children's Medical Center