sepsis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of sepsis3.0; 2. Age =18 years and age =80 years; 3.ICU admission time > 24 hours;
Exclusion criteria
Exclusion criteria: 1. Age 80 years; 2. Patients diagnosed with malignant tumors; 3. Existing or new central nervous system diseases; 4. Diagnosed mental illness; 5. Patients during pregnancy and lactation; 6. Impaired consciousness, hearing and vision, etc., unable to complete the scale test; 7. Situations that the researcher deems inappropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CAM-ICU score;MoCA score;HADS score;IES-R score;Peripheral blood proteomic detection;Genomic testing of peripheral blood;Fecal pathogen spectrum detection;Detection of fecal microecology;MRI imaging of the brain; | — |
Secondary
| Measure | Time frame |
|---|---|
| heart rate;arterial pressure;temperature;respiratory rate;oxygenation index;GCS score;APACHE ? score;SOFA score;Shock time;Duration of mechanical ventilation;Treatment outcome;blood routine examination;liver function;renal function;Arterial blood gas;lactic acid;coagulation function; | — |
Countries
China
Contacts
Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science and Technology