Psoriasis Vulgaris
Conditions
Interventions
The intervention group:Chinese herbal medicine external application (Fuzhenghefuzhiyang granules) plus topical urea cream
The control group:Placebo granules external application plus topical urea cream
Sponsors
Guangdong Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed with psoriasis vulgaris 2. PASI < 10 or BSA < 10% 3. The age is between 18 and 65 years 4. Written informed consent is provided
Exclusion criteria
Exclusion criteria: 1. Currently are pregnant or lactating 2. Currently have uncontrolled or severe diseases, such as cardiovascular, respiratory, digestive, urinary, haematological or psychiatric diseases; have any known malignancy or a history of malignancy 3. Are allergic to the medications used in this study 4. Currently are participating in other clinical trial(s), or have participated in other clinical trial(s) in the previous month 5. Have not completed the required wash-out requirements of other psoriasis therapies as listed below: topical agents, antimicrobials, phototherapies, systemic nonbiologic therapies, and biologics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Psoriasis Area and Severity Index (PASI);Trial feasibility; | — |
Secondary
| Measure | Time frame |
|---|---|
| At least 50% reduction from baseline PASI score;At least 75% reduction from baseline PASI score;Physician Global Assessment (PGA);Body Surface Area (BSA);Dermatology Life Quality Index (DLQI);Skindex-16;Itch visual analogue scale (VAS);The relapse rate;Safety assessments; | — |
Countries
China
Contacts
Public ContactChuanjian Lu
Guangdong Provincial Hospital of Chinese Medicine
Outcome results
None listed