chronic obstructive pulmonary disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Patients with chronic obstructive pulmonary disease are in a clinically stable period; (2) Patients with periodontal disease are divided into moderate-severe; (3) 40 years old= age = 75 years old; (4) Clear consciousness, able to complete the questionnaire survey and cardiopulmonary function, periodontal condition assessment / examination;
Exclusion criteria
Exclusion criteria: (1) Have other systemic diseases such as bronchial asthma, heart disease, diabetes, kidney disease, liver function impairment and so on; (2) Have taken various anti-inflammatory drugs, immune preparations, systemic glucocorticoids, etc. in the past 3 months; (3) Have undergone periodontal treatment (cleansing, scraping, periodontal surgery, etc.) within 3 months; (4) There are less than 20 teeth left in the mouth or no remaining teeth in the mouth; (5) There is a history of coronary prosthesis or orthodontic treatment in the oral cavity; (6) Pregnant and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differential metabolites of saliva; | — |
Countries
China