Characteristics of intestinal microflora and metabolites in idiopathic membranous nephropathy patients with spleen deficiency syndrome

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2200064050

Enrollment

Unknown

Registered

2022-09-24

Start date

2022-09-28

Completion date

Unknown

Last updated

2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Idiopathic membranous nephropathy

Interventions

Spleen deficiency group:Nothing

Non spleen deficiency syndrome group:Nothing

Healthy people group:Nothing

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) The pathological diagnosis of renal biopsy is MN or positive for anti PLA2R antibody; (2) Urinary protein quantification is between 1-8g/24h; (3) Blood pressure can be effectively controlled at = 140/90mmHg; (4) eGFR=45ml/min; (5) Age range from 18 to 70 years old, regardless of gender; (6) Not using antibiotics or probiotics in the past month; (7) Body mass index (BMI) between 18.5 and 28.5 kg/m2; (8) Sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients who refused to sign informed consent; 2.There are other situations that are not suitable for entry into the study.

Design outcomes

Primary

Measure	Time frame
Progress-free survival, PFS;	—

Secondary

Measure	Time frame
Overall survival, OS; local progression free survival;regional progression free survival;distant metastasis-free survival, DMFS;disease control rate;objective response rate;toxicity;	—

Countries

China

Contacts

Public ContactLang Rui

langrui621@sina.com13810839088

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026