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Continuous theta-burst stimulation (cTBS) in the treatment of essential tremor (ET): a double-blind, randomized, controlled clinical trial

Continuous theta-burst stimulation (cTBS) in the treatment of essential tremor (ET): a double-blind, randomized, controlled clinical trial

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200064037
Enrollment
Unknown
Registered
2022-09-24
Start date
2022-09-20
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Essential tremor

Interventions

experimental group :cTBS stimulation

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: a. Han patients over 18 years old who met the ET diagnostic criteria in the 2017 IPMDS Tremor Consensus (2017 version), and ET patients who met the tremor classification criteria of Grade 1 and above proposed by the idiopathic tremor research group of the National Institutes of Health in 1996, were definitely diagnosed by at least two neurodegenerative disease experts; b. Volunteer to participate in the study, be able to complete all clinical evaluations, be willing to accept follow-up and sign the informed consent form.

Exclusion criteria

Exclusion criteria: a. CTBS contraindications (e.g., pacemaker installation, metal foreign bodies in the head, etc.); b. Complicated with nervous system diseases except ET; c. Patients with epilepsy, active tumor disease, history of severe mental disease or severe cognitive impairment (including dementia patients).

Design outcomes

Primary

MeasureTime frame
scores of Fahn-Talosa-Marin Tremor Rating Scale (FTM-TRS);

Secondary

MeasureTime frame
Electrophysiological parameters;activities of daily living assement;

Countries

China

Contacts

Public ContactYanming Xu

Department of Neurology, West China Hospital, Sichuan University

neuroxym999@163.com+8618980601677

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026