Dry eye
Conditions
Interventions
Normal group:Nil
Dry eye group: Nil
Sponsors
Eye Institute of Xiamen University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) Fully understand the study and voluntarily sign the ICF; willing to follow and able to complete all trial procedures. 2) 18 years old 10s seconds, Schirmer I test greater than 10mm/5min
Exclusion criteria
Exclusion criteria: 1) Patients with keratitis, conjunctivitis, severe blepharitis and other serious ocular surface diseases that affect the evaluation of efficacy; 2) Patients with acute eye diseases such as macular degeneration, glaucoma, and retinal vascular embolism; 3) Patients with lacrimal duct obstruction, obvious proptosis, and severe corneal decompensation; 4) Patients with severe dry eye or fluorescein stained punctate staining, combined with filamentous matter and ulcer; 5) Those who have had eye surgery or eye trauma within the past 6 months; 6) Those who are using other topical or systemic drugs except artificial tears, and those who use artificial tears 2 hours before the examination; 7) Patients with serious primary diseases such as cardiovascular, liver, kidney and hematopoietic system and systemic immune diseases; 8) Pregnant, lactating women, menopausal women on hormone replacement therapy; 9) Those who have participated in other clinical trials within the past 1 month; 10) Have a history of alcohol and drug abuse; 11) Patients who cannot cooperate or who are mentally ill, and the researchers believe that they are not suitable to participate in this clinical trial. 12) Exit the experiment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TBUT;Corneal staining scores;Schirmer I test;cGAS protein levels;STING protein levels; | — |
Countries
China
Contacts
Public ContactZuguo,Liu
Outcome results
None listed