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Transcranial direct current stimulation improves empathy for pain in healthy population: A randomized, double-blind, sham-controlled, and three-arm parallel study based on ERP

Transcranial direct current stimulation improves empathy for pain in healthy population: A randomized, double-blind, sham-controlled, and three-arm parallel study based on ERP

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200063993
Enrollment
Unknown
Registered
2022-09-22
Start date
2022-09-27
Completion date
Unknown
Last updated
2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Control group:sham stimulation
Experimental group 1:1mA anodal stimulation
Experimental group 2:2mA anodal stimulation

Sponsors

The Sixth Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Right-handed healthy adults aged 18-35 years; 2. The self-rating anxiety scale (standard score <50) and self-rating depression scale (standard score <50) were normal; 3. Have not participated in the previous EEG psychological experiment.

Exclusion criteria

Exclusion criteria: 1. Severe cardiovascular disease; 2. Severe scalp trauma, extensive or open craniocerebral trauma, unable to place electrodes or may cause infection; 3. Brain tissue injury and disease; 4. Mental and mental illness; 5. Patients with malignant tumor and rheumatoid disease; 6. Pregnant or lactating patients; 7. Patients who have not given informed consent or are participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Pain intensity rating;

Secondary

MeasureTime frame
Self-unpleasantness rating;Accuracy and reaction time;N1, N2, P3, LPP amplitudes;

Countries

China

Contacts

Public ContactWang Yuling
wangyul@mail.sysu.edu.cn+86 13922375587

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026