Associations of diet choline intake and plasma trimethylamine N-oxide with nonalcoholic fatty liver disease

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200063974

Enrollment

Unknown

Registered

2022-09-22

Start date

2022-09-26

Completion date

Unknown

Last updated

2023-04-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nonalcoholic fatty liver disease (NAFLD)

Interventions

Control group:red meat dietary pattern+white meat dietary pattern

Experimental group:red meat dietary pattern+white meat dietary pattern

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria of healthy people: patients without fatty liver and other liver diseases were included according to the standards of residents in healthy communities. 2. Inclusion criteria for NAFLD patients: According to the diagnostic criteria for NAFLD, patients with NAFLD were diagnosed by abdominal B-ultrasound.

Exclusion criteria

Exclusion criteria: 1. Patients diagnosed with diabetes/coronary heart disease/stroke/tumor/cirrhosis/renal insufficiency and other important diseases; 2. Patients who are taking drugs that affect blood pressure, blood lipids and glucose metabolism, people with cognitive disabilities, and people who have allergies or intolerances to food in dietary intervention.

Design outcomes

Primary

Measure	Time frame
plasma trimethylamine N-oxide;	—

Secondary

Measure	Time frame
urine trimethylamine N-oxide;plasma choline;	—

Countries

China

Contacts

Public ContactLiu Yan

liuyan_smu@qq.com+86 13570469574

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026