None listed
Conditions
Interventions
Conventional Anesthesia Group:Anesthesia induction and maintenance were performed with sufentanil and remifentanil
Opioid-Free Anesthesia Group:Anesthesia induction and maintenance were performed with dexmetomidine and esketamine
Sponsors
General Hospital of Tibet Military Command
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-60 years who are undergoing laparoscopic surgery under general anesthesia; 2. ASA I or II; 3. No previous history of surgical anesthesia; 4. No chemotherapy or radiotherapy was performed before surgery; 5. No severe nausea and vomiting before surgery; 6. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Unable to understand and cooperate with the questionnaire survey of postoperative visit; 2. The plateau residence history is less than one year; 3. Long-term use of analgesic or sedative drugs; 4. Allergic to any drug in the trial; 5. Patients with a history of hypertension or other serious chronic diseases; 6. Pregnant or lactating.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean arterial pressure;Heart rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Awakening time;Ramsay sedation score;Visual analogue scale pain score;Visual analogue scale of postoperative nausea and vomiting;Postoperative satisfaction score; | — |
Countries
China
Contacts
Public ContactTu Ke
General Hospital of Tibet Military Command
Outcome results
None listed