overweight/obesity
Conditions
Interventions
pomegranate juice group:pomegranate juice treatment
pomegranate juice combined with inulin group:pomegranate juice combined with inulin treatment
Sponsors
The First Affiliated Hospital of Air Force Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: 25<=BMI<=35 kg/m^2, aged 18-55 years.
Exclusion criteria
Exclusion criteria: 1. Patients with chronic diseases such as liver and kidney failure, cancer, diabetes, etc.; 2. History of gastrointestinal surgery; 3. During pregnancy or lactation; 4. Allergic to pomegranate juice and inulin; 5. Adopt a special diet or exercise regimen to control weight; 6. Use probiotics, dietary fiber supplements, or antibiotics, use any medications that affect glucose or fat metabolism, and use laxatives during the 6 weeks prior to or during the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| index of intestinal microbial diversity; | — |
Secondary
| Measure | Time frame |
|---|---|
| body weight;body fat rate;waist-hip ratio;body mass index;fasting blood glucose;insulin;glycosylated hemoglobin;blood triglyceride;blood total cholesterol;blood low density lipoprotein cholesterin;blood high density lipoprotein cholesterin;blood apolipoprotein A;blood apolipoprotein B;blood oxidized LDL cholesterol;blood lipopolysaccharide;blood interleukin 6;blood tumor necrosis factor a;blood high-sensitivity C-reactive protein;blood leptin;blood adiponectin;blood alanine transaminase;blood aspartate aminotransferase;blood short chain fatty acid;blood pomegranate polyphenols;fecal short chain fatty acids;fecal pomegranate polyphenols; | — |
Countries
China
Contacts
Public ContactWei Hongliang
The First Affiliated Hospital of Air Force Medical University
Outcome results
None listed